Micky van de Ven Double Halts The Toffees' Unbeaten Streak at Brand New Home Ground
The Dutch defender emerged as the first defender to score twice in a Premier League match for Spurs since Jan Vertonghen in spring 2013.
Match summary
Micky Van de Ven nods into the net two times in opening period
Everton's defender has equalizer ruled after VAR review
Senegalese midfielder scores third in dying moments
This loss is the Merseyside club's first at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Tottenham extended their winning streak in away games in the top division and delivered the Toffees their first defeat at Hill Dickinson Stadium.
Everton were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after 133 years at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman struck on two occasions from set-pieces in the opening 45 minutes to place their strong form at risk, and they were unable to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - nodded in a third to put the game to bed.
Jake O'Brien thought he had levelled the scores a short while after Van de Ven's first goal, glancing a powerful header past the Spurs keeper from an set-piece.
Beto, meanwhile, missed a number of chances, while the Italian goalkeeper made a succession of excellent stops to ensure the London club went five matches on the road unbeaten in the English top flight.
But the VAR stepped in, advising Craig Pawson to review the goal on the pitchside monitor and the referee decided that the winger and Iliman Ndiaye were in an illegal position and had impeded with the Spurs keeper.
The win elevates Thomas Frank's side up to third in the Premier League, a handful of points off north London rivals and table-toppers the Gunners.
Everton stay 14th and are half a dozen points ahead of the drop zone.
Tottenham analysis: Van de Ven fulfils duties at each end of the field
Following a drab weekday performance in the European competition against the French side, where they managed a mere attempts on target, Frank chose Randal Kolo Muani in attack instead of ex-Everton forward the Brazilian.
The new arrival was unable to make much of an impact before being substituted for the substitute after an hour on the pitch, but it turns out he proved unnecessary in the final outcome.
Defender the Dutchman converted into an offensive threat to be reckoned with.
Tottenham's first goal came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball back across the six-yard box for an unmarked Van de Ven to score.
And Ven de Ven - stepping up as skipper in the Argentine's absence - added his next goal in first-half stoppage time as he rose above the England keeper to head home.
The Dutchman was equally outstanding in defence, partnering effectively with his defensive colleague as the pair dealt excellently with the numerous deliveries thrown their way by Everton.
Toffees breakdown: Toffees missing striker's instinct
Everton's recent stadium had been a fortress, but it appears the novelty may have worn off somewhat and fans headed to the exits after the midfielder's third for Tottenham.
The end in Everton's unbeaten home run won't be a major concern for the manager, but their striker situation are.
The forward and Thierno Barry - the Toffees' pair of recognised centre-forwards - had scored only one league goal between them before the weekend's match.
And they were unable to add to that miserable tally on a damp and dreary evening on in Liverpool.
Beto's form was epitomized when he chose to overhead kick a clear chance from near the goal, despite having space and time to reposition for a more conventional shot that would have tested the keeper.
The substitute, too, failed to influence the game after coming on for Beto in the second half.
It wasn't for a shortage of opportunity. Most of Everton's attacks came through the winger and Ndiaye, who tirelessly whipped dangerous crosses into the Spurs penalty area.
Upcoming fixtures for both teams?
The Toffees: Moyes' men travel to Sunderland in the top flight on early November at 20:00 GMT.
Spurs: The London club go to Newcastle's ground on late October for their fourth-round League Cup match against the Magpies.